Market research

For retail sale medicaments with alkaloids market in North Macedonia, 2026

Release date: Mar 29, 2026

Submission: 15 minutes after payment

Research period: 2017-2025

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File format: docx, xlsx

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Earlier Report Observations

The market for packed retail sale medicaments containing alkaloids in North Macedonia followed a volatile path from 2018 to 2024. After a moderate contraction in 2019, volume expanded strongly through 2021, reaching a peak of 43 913 thousand US dollars. A correction in 2022 reduced the market to 40 339 thousand US dollars, but a recovery followed, lifting the market size to 44 332 thousand US dollars by 2024.

The regulatory and policy environment, as outlined in the 2022 national drug situation overview, shaped the pharmaceutical market during this period, likely influencing the post-2021 adjustment. In 2024, the state-owned manufacturer Alkaloid AD Skopje invested $1 million to facilitate the introduction of biosimilar drugs, marking a strategic move into a new product segment that coincided with the market's return to growth.

Table of content

1. Disclaimer
2. Terms of use of the report
3. Product codes in the statistical classifications used in the report
4. Key Market Indicators and Trends
1. 4.1. Key Market Indicators
  1. 4.1.1. In value
    1. 4.1.1.1. Production, 2018-2022, 2024
    2. 4.1.1.2. Imports, 2018-2024
    3. 4.1.1.3. Exports, 2018-2024
    4. 4.1.1.4. Market size, 2018-2022, 2024
2. 4.2. Market Trends and Factors
5. Production
1. 5.1. Production in North Macedonia
  1. 5.1.1. In value, 2018-2022, 2024, K $ US
2. 5.2. Production in the EU, 2018-2024
  1. 5.2.1. In value, 2018-2024, K $ US
6. Exports
1. 6.1. Exports (Direct Data)
  1. 6.1.1. Exports - Total information
  2. 6.1.2. Exports in kind, t
    1. 6.1.2.1. Annual dynamics of product's exports from North Macedonia in kind, 2018-2024, t
    2. 6.1.2.2. Dynamics of product's exports in kind from North Macedonia by countries, 2018-2024, t
    3. 6.1.2.3. Structure of product's exports in kind by countries, 2018-2024
  3. 6.1.3. Exports in value, K $ US
    1. 6.1.3.1. Annual dynamics of product's exports from North Macedonia in value, 2018-2024, K $ US
    2. 6.1.3.2. Dynamics of product's exports in value from North Macedonia by countries, 2018-2024, K $ US
    3. 6.1.3.3. Structure of product's exports in value by countries, 2018-2024
  4. 6.1.4. Average price of product's exports, $ US/kg
    1. 6.1.4.1. Annual dynamics of average price of product's exports from North Macedonia, 2018-2024, $ US/kg
    2. 6.1.4.2. Dynamics of average price of product's exports from North Macedonia by countries, 2018-2024, $ US/kg
2. 6.2. Exports (Mirror Data)
  1. 6.2.1. Exports - Total information
  2. 6.2.2. Exports in kind, t
    1. 6.2.2.1. Annual dynamics of product's exports from North Macedonia in kind, 2018-2024, t
    2. 6.2.2.2. Dynamics of product's exports in kind from North Macedonia by countries, 2018-2024, t
    3. 6.2.2.3. Structure of product's exports in kind by countries, 2018-2024
  3. 6.2.3. Exports in value, K $ US
    1. 6.2.3.1. Annual dynamics of product's exports from North Macedonia in value, 2018-2024, K $ US
    2. 6.2.3.2. Dynamics of product's exports in value from North Macedonia by countries, 2018-2024, K $ US
    3. 6.2.3.3. Structure of product's exports in value by countries, 2018-2024
  4. 6.2.4. Average price of product's exports, $ US/kg
    1. 6.2.4.1. Annual dynamics of average price of product's exports from North Macedonia, 2018-2024, $ US/kg
    2. 6.2.4.2. Dynamics of average price of product's exports from North Macedonia by countries, 2018-2024, $ US/kg
7. Imports
1. 7.1. Imports (Direct Data)
  1. 7.1.1. Imports - Total information
  2. 7.1.2. Imports in kind, t
    1. 7.1.2.1. Annual dynamics of product's imports to North Macedonia in kind, 2018-2024, t
    2. 7.1.2.2. Dynamics of product's imports in kind to North Macedonia by countries, 2018-2024, t
    3. 7.1.2.3. Structure of product's imports in kind by countries, 2018-2024
  3. 7.1.3. Imports in value, K $ US
    1. 7.1.3.1. Annual dynamics of product's imports to North Macedonia in value, 2018-2024, K $ US
    2. 7.1.3.2. Dynamics of product's imports in value to North Macedonia by countries, 2018-2024, K $ US
    3. 7.1.3.3. Structure of product's imports in value by countries, 2018-2024
  4. 7.1.4. Average price of product's imports, $ US/kg
    1. 7.1.4.1. Annual dynamics of average price of product's imports to North Macedonia, 2018-2024, $ US/kg
    2. 7.1.4.2. Dynamics of average price of product's imports to North Macedonia by countries, 2018-2024, $ US/kg
2. 7.2. Imports (Mirror Data)
  1. 7.2.1. Imports - Total information
  2. 7.2.2. Imports in kind, t
    1. 7.2.2.1. Annual dynamics of product's imports to North Macedonia in kind, 2018-2024, t
    2. 7.2.2.2. Dynamics of product's imports in kind to North Macedonia by countries, 2018-2024, t
    3. 7.2.2.3. Structure of product's imports in kind by countries, 2018-2024
  3. 7.2.3. Imports in value, K $ US
    1. 7.2.3.1. Annual dynamics of product's imports to North Macedonia in value, 2018-2024, K $ US
    2. 7.2.3.2. Dynamics of product's imports in value to North Macedonia by countries, 2018-2024, K $ US
    3. 7.2.3.3. Structure of product's imports in value by countries, 2018-2024
  4. 7.2.4. Average price of product's imports, $ US/kg
    1. 7.2.4.1. Annual dynamics of average price of product's imports to North Macedonia, 2018-2024, $ US/kg
    2. 7.2.4.2. Dynamics of average price of product's imports to North Macedonia by countries, 2018-2024, $ US/kg
8. Trade balance
1. 8.1. Trade balance (Direct Data)
  1. 8.1.1. In kind, t
  2. 8.1.2. In value, K $ US
2. 8.2. Trade balance (Mirror Data)
  1. 8.2.1. In kind, t
  2. 8.2.2. In value, K $ US
9. Top buying and selling countries, 2018-2024
1. 9.1. Direct Data
  1. 9.1.1. Import in Value by Countries-buyers
  2. 9.1.2. Export in Value by Countries-suppliers
2. 9.2. Mirror Data
  1. 9.2.1. Import in Value by Countries-buyers
  2. 9.2.2. Export in Value by Countries-suppliers

Production for retail sale medicaments with alkaloids in North Macedonia

In value, 2017-2020, K $ US

In 2020, North Macedonia's output of retail sale medicaments with alkaloids was valued at 44 227 thousand US dollars, marking a 13.5% increase compared to 2019. The largest decline occurred in 2019, at 3.4%, while the largest increase was recorded in 2018, at 18.6%. Over the period from 2017 to 2020, production grew by 29.9%, which translates to an annualized growth rate of 9.1%.

Annual dynamics of production in North Macedonia in value, 2017-2020, K $ US

Parameter		2018	2019	2020	CAGR
1	Change from last year	18.6%	(3.4%)	13.5%	9.1%

Source: SHEV.io

Exports for retail sale medicaments with alkaloids from North Macedonia

Exports in kind, t

North Macedonia's export volume of retail sale medicaments with alkaloids increased for the third consecutive year in 2020, reaching 186.1 tonnes. This represents a significant rise of 62.7% from the previous year. From 2017 to 2020, exports surged by 149.2%, with an annualized growth rate of 35.6%.

Annual dynamics of product's exports from North Macedonia in kind, 2017-2020, t

Parameter		2018	2019	2020	CAGR
1	Change from last year	33.9%	14.4%	62.7%	35.6%

Source: SHEV.io

Between 2017 and 2020, Slovenia, Croatia, and Serbia were the primary buyers of retail sale medicaments with alkaloids from North Macedonia, accounting for 22.8%, 15.6%, and 15.6% of exports in kind, respectively. Together, these three countries made up 54.0% of total exports in kind.

Structure of product's exports in kind by countries, 2017-2020

Source: SHEV.io

World map of product's exports from North Macedonia in kind, 2017-2020

Source: SHEV.io

Exports in value, K $ US

In 2020, North Macedonia's exports of retail sale medicaments with alkaloids totaled 9 985 thousand US dollars, showing a 30.3% increase compared to 2019. The largest decline was in 2019, at 8.4%, while the largest increase occurred in 2018, at 42.1%. Over the 2017-2020 period, exports grew by 69.7%, with a compound annual growth rate of 19.3%.

Annual dynamics of product's exports from North Macedonia in value, 2017-2020, K $ US

Parameter		2018	2019	2020	CAGR
1	Change from last year	42.1%	(8.4%)	30.3%	19.3%

Source: SHEV.io

From 2017 to 2020, Serbia, France, and Slovenia were the top buyers of retail sale medicaments with alkaloids from North Macedonia in value terms, with shares of 42.0%, 11.4%, and 10.9%, respectively. Their combined share reached 64.2% of total exports in value terms.

Structure of product's exports in value by countries, 2017-2020

Source: SHEV.io

World map of product's exports from North Macedonia in value, 2017-2020

Source: SHEV.io

Imports for retail sale medicaments with alkaloids to North Macedonia

Imports in kind, t

In 2020, North Macedonia imported 22.0 tonnes of retail sale medicaments with alkaloids, which was 13.4% lower than in 2019. The largest decline was recorded in 2018, at 20.2%, while the largest increase occurred in 2019, at 2.1%. Between 2017 and 2020, imports decreased by 29.5%, with an annualized decline rate of 11.0%.

Annual dynamics of product's imports to North Macedonia in kind, 2017-2020, t

Parameter		2018	2019	2020	CAGR
1	Change from last year	(20.2%)	2.1%	(13.4%)	(11.0%)

Source: SHEV.io

During 2017-2020, Slovenia, Bosnia and Herzegovina, and Serbia led the import structure in kind for retail sale medicaments with alkaloids in North Macedonia, with shares of 39.6%, 34.4%, and 10.7%, respectively. Together, they accounted for 84.7% of total imports in kind.

Structure of product's imports in kind by countries, 2017-2020

Source: SHEV.io

World map of product's imports to North Macedonia in kind, 2017-2020

Source: SHEV.io

Imports in value, K $ US

In 2020, North Macedonia's imports of retail sale medicaments with alkaloids amounted to 3 852 thousand US dollars, an 11.9% increase from 2019. The minimum value was recorded in 2019 at 3 442 thousand US dollars, while the maximum was in 2018 at 4 080 thousand US dollars. The largest decline occurred in 2019, at 15.6%.

Annual dynamics of product's imports to North Macedonia in value, 2017-2020, K $ US

Parameter		2018	2019	2020	CAGR
1	Change from last year	7.8%	(15.6%)	11.9%	0.6%

Source: SHEV.io

From 2017 to 2020, France, Slovenia, and Bosnia and Herzegovina were the key sources for imports in value terms of retail sale medicaments with alkaloids in North Macedonia, with shares of 53.9%, 14.4%, and 11.1%, respectively. Their combined share made up 79.4% of total imports in value terms.

Structure of product's imports in value by countries, 2017-2020

Source: SHEV.io

World map of product's imports to North Macedonia in value, 2017-2020

Source: SHEV.io