Not for retail sale medicaments with alkaloids market in Spain

Earlier Report Observations

The market for not for retail sale medicaments with alkaloids in Spain expanded from $9.6 million in 2018 to $12.1 million in 2019. It then contracted to $10.9 million in 2020, a shift that occurred alongside widespread supply issues in the Spanish pharmaceutical sector where plant capacity constraints, rising demand, and manufacturing problems disrupted availability.

After 2020, import values rose to $0.7 million in 2021 and reached $1.3 million in 2022, a period marked by strict regulatory oversight from the Spanish Agency of Medicines and Medical Products (AEMPS). Imports fell to $1.0 million in 2023 as supply shortages persisted, affecting 4.6% of drug presentations. A dramatic change followed in 2024, with imports surging to $5.8 million and exports to $2.5 million. This expansion was driven by the entry of seven new medicine production plants, which increased domestic industrial capacity, and the draft of a new Medicines and Medical Products Law proposing reforms for clinical trials, packaging security devices, and orphan drugs.

Production not for retail sale medicaments with alkaloids in Spain

In value, 2017-2020, K $ US

Spain's production of not-for-retail-sale medicaments containing alkaloids declined after two years of growth. In 2020, output was valued at 10 738 thousand US dollars, marking a 14.8% decrease from the previous year. Production had increased by 50.5% between 2017 and 2020, averaging an annual growth rate of 14.6%. The peak value was recorded in 2019 at 12 609 thousand US dollars, with the largest annual increase of 41.0% also occurring that year.

Annual dynamics of production in Spain in value, 2017-2020, K $ US

Exports not for retail sale medicaments with alkaloids from Spain

Exports in kind, kg

The market exhibited significant volatility during this period. Exports reached their lowest point in 2017 and peaked in 2019, with a 2 735-fold difference between these years. In 2020, Spain exported 1 022 kilograms of not-for-retail-sale medicaments with alkaloids, representing a gradual decline of 6.6% from the previous year. The maximum volume was recorded in 2019 at 1 094 kilograms, while the largest annual increase of 43 400.0% occurred in 2018.

Annual dynamics of product's exports from Spain in kind, 2017-2020, kg

From 2017 to 2020, Portugal, Italy, and Poland consistently led Spain's export destinations by volume. Portugal accounted for 47.3% of exports, Italy for 13.0%, and Poland for 10.2%. Together, these three countries represented 70.6% of total export flows.

Structure of product's exports in kind by countries, 2017-2020

World map of product's exports from Spain in kind, 2017-2020

Exports in value, K $ US

Market behavior was highly volatile during these years. Export values dropped to their lowest in 2017 and surged to a peak in 2019, with a 16 929-fold difference between these extremes. In 2020, Spain's exports of not-for-retail-sale medicaments with alkaloids were valued at 379 thousand US dollars, reflecting a sharp 60.4% decrease from 2019. The maximum value was recorded in 2019 at 956 thousand US dollars, while the largest annual increase of 517 962.1% occurred in 2018.

Annual dynamics of product's exports from Spain in value, 2017-2020, K $ US

Between 2017 and 2020, Portugal, Italy, and Lithuania emerged as the primary markets for Spain's exports by value. Portugal accounted for 27.1% of export value, Italy for 16.3%, and Lithuania for 10.9%. Collectively, these three countries represented 54.3% of total export flows.

Structure of product's exports in value by countries, 2017-2020

World map of product's exports from Spain in value, 2017-2020

Imports not for retail sale medicaments with alkaloids to Spain

Imports in kind, kg

Spain's imports of not-for-retail-sale medicaments with alkaloids increased for the third consecutive year. In 2020, imports reached 29 923 kilograms, a substantial 249.3% rise from the previous year. Between 2017 and 2020, imports grew by 1 305.6%, averaging an annual growth rate of 141.3%.

Annual dynamics of product's imports to Spain in kind, 2017-2020, kg

From 2017 to 2020, Germany, France, and Denmark were the leading suppliers of not-for-retail-sale medicaments with alkaloids to Spain by volume. Germany accounted for 31.2% of imports, France for 28.4%, and Denmark for 15.7%. Together, these three countries made up 75.3% of total import volume.

Structure of product's imports in kind by countries, 2017-2020

World map of product's imports to Spain in kind, 2017-2020

Imports in value, K $ US

After a two-year decline, Spain's imports of not-for-retail-sale medicaments with alkaloids increased in value. In 2020, imports totaled 403 thousand US dollars, showing a steep 41.3% rise from the previous year. Over the 2017-2020 period, imports decreased by 76.9%, with an average annual decline of 38.7%. The lowest value was recorded in 2019 at 403 thousand US dollars, while the largest annual decrease of 62.9% occurred in 2018.

Annual dynamics of product's imports to Spain in value, 2017-2020, K $ US

During 2017-2020, the United Kingdom, Denmark, and the Netherlands formed the main cluster of markets for Spain's imports by value. The United Kingdom accounted for 55.4% of import value, Denmark for 16.5%, and the Netherlands for 6.7%. Together, these three countries represented 78.6% of total import flows.

Structure of product's imports in value by countries, 2017-2020

World map of product's imports to Spain in value, 2017-2020